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The antibody against IGHG3 was raised in rabbit using the Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against IGHG3 was raised in rabbit using the Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
Western Blot | Positive WB detected in human serum | All lanes:IGHG3 antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 42 kDa | Observed band size: 42 kDa
| Cat.No | ADC-00384A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IGHG3 |
| Target Synonyms | IGHG3Immunoglobulin heavy constant gamma 3 antibody; HDC antibody; Heavy chain disease protein antibody; Ig gamma-3 chain C region antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01860 |
Uniprot Id
P01860
Target Species
Human
Target Name
IGHG3
Target Full Name
Immunoglobulin heavy constant gamma 3
Target Function
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Target Subcellular Location
Secreted. Cell membrane.
Target Synonyms
IGHG3Immunoglobulin heavy constant gamma 3; HDC; Heavy chain disease protein; Ig gamma-3 chain C region
Target Background
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Involved in retina homeostasis. Located in blood microparticle and extracellular exosome.
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