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The antibody against IL10RB was raised in rabbit using the Fusion protein of Human IL10RB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against IL10RB was raised in rabbit using the Fusion protein of Human IL10RB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-32402A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IL10RB |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human IL10RB | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q08334 |
Uniprot Id
Q08334
Target Species
Human
Target Name
IL10RB
Target Full Name
Interleukin-10 receptor subunit beta
Target Function
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
Target Involvement
Inflammatory bowel disease 25 (IBD25)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Type II cytokine receptor family
Target Synonyms
Cd210 ; CDw210b; CRF2 4; CRF2-4; CRFB4; Cytokine receptor class II ; Cytokine receptor class II CRF2 4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; Cytokine receptor family II member 4 ; D21S58; D21S66; I10R2_HUMAN; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; IL10R2; IL10RB; Interleukin 10 receptor beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta
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