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The antibody against IL34 was raised in rabbit using the Recombinant Human Interleukin-34 protein (191-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against IL34 was raised in rabbit using the Recombinant Human Interleukin-34 protein (191-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-10350A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IL34 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Interleukin-34 protein (191-240AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6ZMJ4 |
Uniprot Id
Q6ZMJ4
Target Species
Human
Target Name
IL34
Target Full Name
Interleukin-34
Target Function
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
Target Subcellular Location
Secreted.
Target Protein Families
IL-34 family
Target Tissue Specificity
Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate
Target Synonyms
C16orf77; Chromosome 16 open reading frame 77; FPT025; IL 34; IL-34; Il34; IL34_HUMAN; Interleukin 34; Interleukin-34; Interleukin34; MGC34647
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