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The antibody against IL5RA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against IL5RA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01190A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IL5RA |
| Target Synonyms | IL5R; CD125; CDw125; HSIL5R3; IL5RA | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | B cells, HL-60, Mouse liver, Mouse lung, Rat lung, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q01344 | Immunogen Sequence |
Uniprot Id
Q01344
Target Species
Human
Target Name
IL5RA
Target Full Name
Interleukin-5 receptor subunit alpha
Target Function
This is the receptor for interleukin-5. The alpha chain binds to IL5.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Type I cytokine receptor family, Type 5 subfamily
Target Tissue Specificity
Expressed on eosinophils and basophils.
Target Synonyms
IL5R; CD125; CDw125; HSIL5R3; IL5RA
Target Background
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
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