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Rabbit anti-Human INADL Polyclonal Antibody

The antibody against INADL was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 450-680 of human INADL (NP_795352.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01298A

The antibody against INADL was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 450-680 of human INADL (NP_795352.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01298A ClonalityPolyclonal
Host SpeciesRabbitTarget NameINADL
Target SynonymsCipp; INADL; hINADL; InaD-likeFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, 293T, SKOV3, SW480ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 450-680 of human INADL (NP_795352.2).Target SpeciesHuman
Uniprot IDQ8NI35Immunogen Sequence
Background Information
  • Uniprot Id

    Q8NI35

  • Target Species

    Human

  • Target Name

    PATJ

  • Target Full Name

    InaD-like protein

  • Target Function

    Scaffolding protein that facilitates the localization of proteins to the cell membrane. Required for the correct formation of tight junctions and epithelial apico-basal polarity. Positively regulates epithelial cell microtubule elongation and cell migration, possibly via facilitating localization of PRKCI/aPKC and PAR3D/PAR3 at the leading edge of migrating cells. Plays a role in the correct reorientation of the microtubule-organizing center during epithelial migration. May regulate the surface expression and/or function of ASIC3 in sensory neurons. May recruit ARHGEF18 to apical cell-cell boundaries

  • Target Subcellular Location

    Cell junction, tight junction. Apical cell membrane; Peripheral membrane protein. Cytoplasm, perinuclear region.

  • Target Tissue Specificity

    Expressed in renal tubules (at protein level). Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain.

  • Target Synonyms

    PATJ; CIPP; INADL; InaD-like protein; Inadl protein; hINADL; Channel-interacting PDZ domain-containing protein; Pals1-associated tight junction protein; Protein associated to tight junctions

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