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The antibody against INHBC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 103-352 of human INHBC (NP_005529.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against INHBC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 103-352 of human INHBC (NP_005529.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02430A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INHBC |
| Target Synonyms | IHBC; INHBC | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, BT-474, HT-29, MCF7, Mouse brain, Mouse pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 103-352 of human INHBC (NP_005529.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P55103 | Immunogen Sequence |
Uniprot Id
P55103
Target Species
Human
Target Name
INHBC
Target Full Name
Inhibin beta C chain
Target Function
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family
Target Tissue Specificity
Expressed in benign prostatic hyperplasia.
Target Research Area
Signal Transduction
Target Synonyms
Activin beta C chain; Activin beta-C chain; IHBC; Inhbc; INHBC_HUMAN; Inhibin beta C chain; Inhibin, beta C
Target Background
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate.
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