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The antibody against INPP5A was raised in rabbit using the Human INPP5A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against INPP5A was raised in rabbit using the Human INPP5A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48235A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INPP5A |
| Target Synonyms | 4, 5-trisphosphate 5-phophatase antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human INPP5A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14642 |
Uniprot Id
Q14642
Target Species
Human
Target Name
INPP5A
Target Full Name
Inositol polyphosphate-5-phosphatase A
Target Function
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.
Target Subcellular Location
Cell membrane; Lipid-anchor. Cell projection, dendrite.
Target Protein Families
Inositol 1,4,5-trisphosphate 5-phosphatase type I family
Target Tissue Specificity
Predominantly expressed in heart, brain, and skeletal muscle. In brain; high level in Purkinje cells.
Target Research Area
Signal Transduction
Target Synonyms
4; 43 kDa inositol polyphosphate 5-phophatase; 5-trisphosphate 5-phosphatase; 5PTase; CTCL tumor antigen HD-CL-02; DKFZp434A1721; I5P1; I5P1_HUMAN; Inositol polyphosphate 5 phosphatase; inositol polyphosphate-5-phosphatase A; inositol trisphosphate-5-phosphatase; INPP5A; INPP5A inositol polyphosphate-5-phosphatase; InsP3 5-phosphatase; MGC116947; MGC116949; Type I inositol-1; type I inositol-1,4,5-trisphosphate 5-phophatase
Target Background
The protein encoded by this gene is a membrane-associated type I inositol 1, 4, 5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
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