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The antibody against INSRR was raised in rabbit using the Human INSRR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against INSRR was raised in rabbit using the Human INSRR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48231A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INSRR |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human INSRR | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P14616 |
Uniprot Id
P14616
Target Species
Human
Target Name
INSRR
Target Full Name
Insulin receptor-related protein
Target Function
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
Target Synonyms
INSRR; INSRR_HUMAN; Insulin Receptor R; Insulin receptor related receptor precursor; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; insulin receptor-related receptor; IR R; IR related receptor; IR-related receptor; IRR; Sir r; Sirr
Target Background
Enables transmembrane receptor protein tyrosine kinase activity. Involved in actin cytoskeleton reorganization; cellular response to alkaline pH; and protein autophosphorylation. Part of receptor complex.
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