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Rabbit anti-Human INTS9 Polyclonal Antibody

The antibody against INTS9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 459-658 of human INTS9 (NP_060720.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01558A

The antibody against INTS9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 459-658 of human INTS9 (NP_060720.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01558A ClonalityPolyclonal
Host SpeciesRabbitTarget NameINTS9
Target SynonymsINT9; RC74; CPSF2L; INTS9FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Jurkat, Mouse brain, Mouse liver, Rat testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 459-658 of human INTS9 (NP_060720.2).Target SpeciesHuman
Immunogen SequenceKLLKEVQPLHVVCPEQYTQPPPAQSHRMDLMIDCQPPAMSYRRAEVLALPFKRRYEKIEIMPELADSLVPMEIKPGISLATVSAVLHTKDNKHLLQPPPRPAQPTSGKKRKRVSDDVPDCKVLKPLLSGSIPVEQFVQTLEKHGFSDIKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEMLRVRLRDLVLKFLQKFUniprot IDQ9NV88
Background Information
  • Uniprot Id

    Q9NV88

  • Target Species

    Human

  • Target Name

    INTS9

  • Target Full Name

    Integrator complex subunit 9

  • Target Function

    Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, INTS9 subfamily

  • Target Synonyms

    CPSF; CPSF2; CPSF2L; FLJ10871; Int9; INT9_HUMAN; Integrator complex subunit 9; INTS 9; INTS9; Protein related to CPSF subunits of 74 kDa; RC 74; RC-74; RC74; Related to CPSF subunits 74 kDa

  • Target Background

    This gene encodes a subunit of the Integrator complex. This protein complex binds the C-terminal domain of RNA polymerase II and likely plays a role in small nuclear RNA processing. The encoded protein has similarities to the subunits of the cleavage and polyadenylation specificity factor complex. Alternatively spliced transcript variants have been described.

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