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The antibody against INTS9 was raised in rabbit using the Recombinant Human Integrator complex subunit 9 protein (368-658AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against INTS9 was raised in rabbit using the Recombinant Human Integrator complex subunit 9 protein (368-658AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-15948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INTS9 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Integrator complex subunit 9 protein (368-658AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NV88 |
Uniprot Id
Q9NV88
Target Species
Human
Target Name
INTS9
Target Full Name
Integrator complex subunit 9
Target Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Target Subcellular Location
Nucleus.
Target Protein Families
Metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, INTS9 subfamily
Target Synonyms
CPSF; CPSF2; CPSF2L; FLJ10871; Int9; INT9_HUMAN; Integrator complex subunit 9; INTS 9; INTS9; Protein related to CPSF subunits of 74 kDa; RC 74; RC-74; RC74; Related to CPSF subunits 74 kDa
Target Background
This gene encodes a subunit of the Integrator complex. This protein complex binds the C-terminal domain of RNA polymerase II and likely plays a role in small nuclear RNA processing. The encoded protein has similarities to the subunits of the cleavage and polyadenylation specificity factor complex. Alternatively spliced transcript variants have been described.
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