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The antibody against IPO9 was raised in rabbit using the Synthetic peptide of Human IPO9 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against IPO9 was raised in rabbit using the Synthetic peptide of Human IPO9 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-26538A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IPO9 |
| Target Synonyms | Imp9 antibody; Imp9a antibody; Imp9b antibody; Importin-9 antibody; Importin-9a antibody; Ipo9 antibody; IPO9_HUMAN antibody; Ran-binding protein 9 antibody; RanBP9 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human IPO9 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96P70 |
Uniprot Id
Q96P70
Target Species
Human
Target Name
IPO9
Target Full Name
Importin-9
Target Function
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of RPS7, RPL18A, RPL6, histone H2A, histone H2B and histone. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. Mediates the nuclear import of actin.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Importin beta family
Target Synonyms
Imp9; Imp9a; Imp9b; Importin-9; Importin-9a; Ipo9; IPO9_HUMAN; Ran-binding protein 9; RanBP9
Target Background
Enables nuclear import signal receptor activity. Involved in protein import into nucleus. Located in cytoplasm.
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