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The antibody against IRAK2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human IRAK2 (NP_001561.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against IRAK2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human IRAK2 (NP_001561.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04278A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRAK2 |
| Target Synonyms | IRAK-2; IRAK2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human IRAK2 (NP_001561.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43187 | Immunogen Sequence |
Uniprot Id
O43187
Target Species
Human
Target Name
IRAK2
Target Full Name
Interleukin-1 receptor-associated kinase-like 2
Target Function
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Target Protein Families
Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily
Target Tissue Specificity
Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Target Research Area
Immunology
Target Synonyms
il1rak2; Interleukin 1 receptor associated kinase 2; Interleukin 1 receptor associated kinase like 2; Interleukin-1 receptor-associated kinase-like 2; IRAK 2; IRAK-2; Irak2; IRAK2_HUMAN; MGC150550
Target Background
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
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