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The antibody against IRAK2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human IRAK-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against IRAK2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human IRAK-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of 293 cells using IRAK-2 Polyclonal Antibody
Western Blot analysis of Jurkat HuvEc cells using IRAK-2 Polyclonal Antibody2
| Cat.No | ADC-38383A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRAK2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human IRAK-2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43187 |
Uniprot Id
O43187
Target Species
Human
Target Name
IRAK2
Target Full Name
Interleukin-1 receptor-associated kinase-like 2
Target Function
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Target Protein Families
Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily
Target Tissue Specificity
Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Target Research Area
Immunology
Target Synonyms
il1rak2; Interleukin 1 receptor associated kinase 2; Interleukin 1 receptor associated kinase like 2; Interleukin-1 receptor-associated kinase-like 2; IRAK 2; IRAK-2; Irak2; IRAK2_HUMAN; MGC150550
Target Background
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
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