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The antibody against IRS2 was raised in rabbit using the Recombinant Human Insulin receptor substrate 2 protein (766-1001AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against IRS2 was raised in rabbit using the Recombinant Human Insulin receptor substrate 2 protein (766-1001AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human pancreatic tissue using IRS2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using IRS2 Antibody at dilution of 1:1002
Immunofluorescent analysis of Hela cells using IRS2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-11046A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRS2 |
| Target Synonyms | Insulin receptor substrate 2 antibody; IRS 2 antibody; IRS-2 antibody; Irs2 antibody; IRS2_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Insulin receptor substrate 2 protein (766-1001AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y4H2 |
Uniprot Id
Q9Y4H2
Target Species
Human
Target Name
IRS2
Target Full Name
Insulin receptor substrate 2
Target Function
May mediate the control of various cellular processes by insulin.
Target Subcellular Location
Cytoplasm, cytosol.
Target Synonyms
Insulin receptor substrate 2; IRS 2; IRS-2; Irs2; IRS2_HUMAN
Target Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
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