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The antibody against ISPD was raised in rabbit using the Recombinant Human Isoprenoid synthase domain-containing protein (1-264AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ISPD was raised in rabbit using the Recombinant Human Isoprenoid synthase domain-containing protein (1-264AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver cancer using ISPD Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using ISPD Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using ISPD Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-15489A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ISPD |
| Target Synonyms | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein antibody; Isoprenoid synthase domain-containing protein antibody; ispD antibody; ISPD_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Isoprenoid synthase domain-containing protein (1-264AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A4D126 |
Uniprot Id
A4D126
Target Species
Human
Target Name
CRPPA
Target Full Name
D-ribitol-5-phosphate cytidylyltransferase
Target Function
Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production.
Target Involvement
Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A7 (MDDGA7); Muscular dystrophy-dystroglycanopathy limb-girdle C7 (MDDGC7)
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
IspD/TarI cytidylyltransferase family, IspD subfamily
Target Tissue Specificity
Ubiquitously expressed, with high expression in brain.
Target Synonyms
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein; Isoprenoid synthase domain-containing protein; ispD; ISPD_HUMAN
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