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Rabbit anti-Human ITIH3 Polyclonal Antibody

The antibody against ITIH3 was raised in rabbit using the Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-04960A

The antibody against ITIH3 was raised in rabbit using the Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-04960A ClonalityPolyclonal
Host SpeciesRabbitTarget NameITIH3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ06033
Background Information
  • Uniprot Id

    Q06033

  • Target Species

    Human

  • Target Name

    ITIH3

  • Target Full Name

    Inter-alpha-trypsin inhibitor heavy chain H3

  • Target Function

    May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    ITIH family

  • Target Research Area

    Others

  • Target Synonyms

    (ITI heavy chain H3)(ITI-HC3)(Inter-alpha-inhibitor heavy chain 3)(Serum-derived hyaluronan-associated protein)(SHAP)

  • Target Background

    This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix through its ability to bind hyaluronic acid. Polymorphisms of this gene may be associated with increased risk for schizophrenia and major depressive disorder. This gene is present in an inter-alpha-trypsin inhibitor family gene cluster on chromosome 3.

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