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The antibody against ITPKB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ITPKB (NP_002212.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ITPKB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ITPKB (NP_002212.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04034A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ITPKB |
| Target Synonyms | IP3K; IP3KB; PIG37; IP3K-B; IP3-3KB; ITPKB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, BT-474, HepG2, Mouse lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ITPKB (NP_002212.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P27987 | Immunogen Sequence |
Uniprot Id
P27987
Target Species
Human
Target Name
ITPKB
Target Full Name
Inositol-trisphosphate 3-kinase B
Target Research Area
Signal Transduction
Target Synonyms
1D myo inositol trisphosphate 3 kinase B; 4; 5-trisphosphate 3-kinase B; Inositol 1 4 5 trisphosphate 3 kinase B; Inositol 1; Inositol trisphosphate 3 kinase B; Inositol-trisphosphate 3-kinase B; InsP 3-kinase B; IP3 3 kinase; IP3 3 kinase B; IP3 3-kinase B; IP3K; IP3K B; IP3KB; IP3KB_HUMAN; Itpkb
Target Background
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
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