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The antibody against JAG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human JAG2 (NP_002217.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against JAG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human JAG2 (NP_002217.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-05777A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | JAG2 |
| Target Synonyms | HJ2; SER2; LGMDR27; JAG2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human JAG2 (NP_002217.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | ARPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGPCSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDE | Uniprot ID | Q9Y219 |
Uniprot Id
Q9Y219
Target Species
Human
Target Name
JAG2
Target Full Name
Protein jagged-2
Target Function
Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney.
Target Synonyms
HJ2; SER2; LGMDR27; JAG2
Target Background
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
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