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The antibody against K-Cadherin (CDH6) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human K-Cadherin (K-Cadherin (CDH6)) (NP_004923.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against K-Cadherin (CDH6) was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human K-Cadherin (K-Cadherin (CDH6)) (NP_004923.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01780A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | K-Cadherin (CDH6) |
| Target Synonyms | CAD6; KCAD; K-Cadherin (CDH6) | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, Mouse brain, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human K-Cadherin (K-Cadherin (CDH6)) (NP_004923.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P55285 | Immunogen Sequence |
Uniprot Id
P55285
Target Species
Human
Target Name
CDH6
Target Full Name
Cadherin-6
Target Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
Target Synonyms
CDH6; Cadherin-6; Kidney cadherin; K-cadherin
Target Background
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
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