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Rabbit anti-Human KANSL1 Polyclonal Antibody, Biotin conjugated

The antibody against KANSL1 was raised in rabbit using the Recombinant Human KAT8 regulatory NSL complex subunit 1 protein (815-1086AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-15284A

The antibody against KANSL1 was raised in rabbit using the Recombinant Human KAT8 regulatory NSL complex subunit 1 protein (815-1086AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-15284A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKANSL1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateBiotin conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human KAT8 regulatory NSL complex subunit 1 protein (815-1086AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ7Z3B3
Background Information
  • Uniprot Id

    Q7Z3B3

  • Target Species

    Human

  • Target Name

    KANSL1

  • Target Full Name

    KAT8 regulatory NSL complex subunit 1

  • Target Function

    As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.

  • Target Subcellular Location

    Nucleus. Nucleus. Chromosome, centromere, kinetochore.

  • Target Tissue Specificity

    Expressed in the brain.

  • Target Synonyms

    CENP-36; centromere protein 36; DKFZp686P06109; DKFZp727C091; hMSL1v1; hypothetical protein LOC284058; K1267_HUMAN; KANSL1; KAT8 regulatory NSL complex subunit 1; KDVS; KIAA1267; male-specific lethal 1 homolog; MGC102843; MLL1/MLL complex subunit KIAA1267; MSL1 homolog 1; MSL1v1; Non specific lethal 1 homolog; NSL complex protein NSL1; NSL1

  • Target Background

    This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The encoded protein has been implicated in a variety of cellular processes including enhancer regulation, cell proliferation, and mitosis. Mutations in this gene are associated with Koolen-de Vries Syndrome.

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