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The antibody against KCNA6 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily A member 6 protein (1-171AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against KCNA6 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily A member 6 protein (1-171AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using KCNA6 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using KCNA6 Antibody at dilution of 1:1002
| Cat.No | ADC-21966A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNA6 |
| Target Synonyms | KCNA6; Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel HBK2; Voltage-gated potassium channel subunit Kv1.6 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Potassium voltage-gated channel subfamily A member 6 protein (1-171AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P17658 |
Uniprot Id
P17658
Target Species
Human
Target Name
KCNA6
Target Full Name
Potassium voltage-gated channel subfamily A member 6
Target Function
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. Homotetrameric channels display rapid activation and slow inactivation.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel family, A (Shaker) (TC 1.A.1.2) subfamily, Kv1.6/KCNA6 sub-subfamily
Target Synonyms
KCNA6; Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel HBK2; Voltage-gated potassium channel subunit Kv1.6
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