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The antibody against KCNG4 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily G member 4 protein (1-218AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against KCNG4 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily G member 4 protein (1-218AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using KCNG4 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using KCNG4 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-13279A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNG4 |
| Target Synonyms | KCNG4; KCNG3; Potassium voltage-gated channel subfamily G member 4; Voltage-gated potassium channel subunit Kv6.4 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Potassium voltage-gated channel subfamily G member 4 protein (1-218AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TDN1 |
Uniprot Id
Q8TDN1
Target Species
Human
Target Name
KCNG4
Target Full Name
Voltage-gated potassium channel regulatory subunit KCNG4
Target Function
Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel family, G (TC 1.A.1.2) subfamily, Kv6.4/KCNG4 sub-subfamily
Target Tissue Specificity
Highly expressed in brain, and at lower levels in liver, small intestine and colon.
Target Synonyms
KCNG4; KCNG3; Potassium voltage-gated channel subfamily G member 4; Voltage-gated potassium channel subunit Kv6.4
Target Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues.
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