Rabbit anti-Human KCNH6 Polyclonal Antibody

The antibody against KCNH6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human KCNH6 (NP_110406.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04993A

Number

Cat.No	ADA-04993A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	KCNH6
Target Synonyms	ERG2; ERG-2; HERG2; Kv11.2; hERG-2; KCNH6	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T	Application	ELISA, WB

Cat.No

ADA-04993A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

KCNH6

Target Synonyms

ERG2; ERG-2; HERG2; Kv11.2; hERG-2; KCNH6

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human KCNH6 (NP_110406.1).	Target Species	Human
Immunogen Sequence	TGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCSSRSLSQRLLSQSFLGSEGSHGRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVT	Uniprot ID	Q9H252

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human KCNH6 (NP_110406.1).

Target Species

Human

Immunogen Sequence

TGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKCSSRSLSQRLLSQSFLGSEGSHGRPGGPGPGTGRGKYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVT

Uniprot ID

Q9H252

Background Information

Uniprot Id

Q9H252
Target Species

Human
Target Name

KCNH6
Target Full Name

Voltage-gated inwardly rectifying potassium channel KCNH6
Target Function

Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.2/KCNH6 sub-subfamily
Target Tissue Specificity

Expressed in prolactin-secreting adenomas.
Target Synonyms

KCNH6; ERG2; Potassium voltage-gated channel subfamily H member 6; Ether-a-go-go-related gene potassium channel 2; ERG-2; Eag-related protein 2; Ether-a-go-go-related protein 2; hERG-2; hERG2; Voltage-gated potassium channel subunit Kv11.2
Target Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms.

Rabbit anti-Human KCNH6 Polyclonal Antibody

Specifications

Immunogen Information

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