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Rabbit anti-Human KCNH7 Polyclonal Antibody, Biotin conjugated

The antibody against KCNH7 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-22658A

The antibody against KCNH7 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-22658A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKCNH7
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateBiotin conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NS40
Background Information
  • Uniprot Id

    Q9NS40

  • Target Species

    Human

  • Target Name

    KCNH7

  • Target Full Name

    Voltage-gated inwardly rectifying potassium channel KCNH7

  • Target Function

    Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily

  • Target Tissue Specificity

    Expressed in prolactin-secreting adenomas.

  • Target Synonyms

    KCNH7; ERG3Potassium voltage-gated channel subfamily H member 7; Ether-a-go-go-related gene potassium channel 3; ERG-3; Eag-related protein 3; Ether-a-go-go-related protein 3; hERG-3; Voltage-gated potassium channel subunit Kv11.3

  • Target Background

    Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.

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