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The antibody against KCNH7 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against KCNH7 was raised in rabbit using the Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-24652A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNH7 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | HRP conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NS40 |
Uniprot Id
Q9NS40
Target Species
Human
Target Name
KCNH7
Target Full Name
Voltage-gated inwardly rectifying potassium channel KCNH7
Target Function
Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily
Target Tissue Specificity
Expressed in prolactin-secreting adenomas.
Target Synonyms
KCNH7; ERG3Potassium voltage-gated channel subfamily H member 7; Ether-a-go-go-related gene potassium channel 3; ERG-3; Eag-related protein 3; Ether-a-go-go-related protein 3; hERG-3; Voltage-gated potassium channel subunit Kv11.3
Target Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
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