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Rabbit anti-Human KCNK3 Polyclonal Antibody

The antibody against KCNK3 was raised in rabbit using the Recombinant Human Potassium channel subfamily K member 3 protein (278-379AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-06870A

The antibody against KCNK3 was raised in rabbit using the Recombinant Human Potassium channel subfamily K member 3 protein (278-379AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-06870A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKCNK3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Potassium channel subfamily K member 3 protein (278-379AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO14649
Background Information
  • Uniprot Id

    O14649

  • Target Species

    Human

  • Target Name

    KCNK3

  • Target Full Name

    Potassium channel subfamily K member 3

  • Target Function

    pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.

  • Target Involvement

    Pulmonary hypertension, primary, 4 (PPH4)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Two pore domain potassium channel (TC 1.A.1.8) family

  • Target Tissue Specificity

    Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.

  • Target Synonyms

    KCNK3; TASK; TASK1; Potassium channel subfamily K member 3; Acid-sensitive potassium channel protein TASK-1; TWIK-related acid-sensitive K(+ channel 1; Two pore potassium channel KT3.1; Two pore K(+ channel KT3.1

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