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The antibody against KHK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human KHK (NP_000212.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KHK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human KHK (NP_000212.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09328A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KHK |
| Target Synonyms | FRUCTU; KHK | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse liver, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human KHK (NP_000212.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P50053 | Immunogen Sequence |
Uniprot Id
P50053
Target Species
Human
Target Name
KHK
Target Full Name
Ketohexokinase
Target Function
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Target Involvement
Fructosuria (FRUCT)
Target Protein Families
Carbohydrate kinase PfkB family
Target Tissue Specificity
Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
Target Research Area
Signal Transduction
Target Synonyms
EC 2.7.1.3; Fructokinase; Hepatic fructokinase; Ketohexokinase; Ketohexokinase isoform a; KHK; KHK_HUMAN
Target Background
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified.
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