Rabbit anti-Human KHSRP Monoclonal Antibody

The antibody against KHSRP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KHSRP (Q92945) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IP, ELISA.

ADA-14012A

Number

Cat.No	ADA-14012A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	KHSRP
Target Synonyms	p75; FBP2; KSRP; FUBP2; KHSRP	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, C2C12, Hep G2, Mouse brain	Application	ELISA, WB, IHC-P, IP

Cat.No

ADA-14012A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

KHSRP

Target Synonyms

p75; FBP2; KSRP; FUBP2; KHSRP

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, C2C12, Hep G2, Mouse brain

Application

ELISA, WB, IHC-P, IP

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KHSRP (Q92945).	Target Species	Human
Immunogen Sequence	MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI	Uniprot ID	Q92945

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KHSRP (Q92945).

Target Species

Human

Immunogen Sequence

MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI

Uniprot ID

Q92945

Background Information

Uniprot Id

Q92945
Target Species

Human
Target Name

KHSRP
Target Full Name

Far upstream element-binding protein 2
Target Function

Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

KHSRP family
Target Tissue Specificity

Detected in neural and non-neural cell lines.
Target Synonyms

Far upstream element-binding protein 2; FBP2; FUBP2; FUBP2_HUMAN; FUSE binding protein 2; FUSE-binding protein 2; KH type splicing regulatory protein (FUSE binding protein 2); KH type splicing regulatory protein; KH type-splicing regulatory protein; KHSRP; KSRP; p75
Target Background

The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).

Rabbit anti-Human KHSRP Monoclonal Antibody

Specifications

Immunogen Information

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