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The antibody against KIAA1324 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 42-300 of human KIAA1324 (NP_001253977.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KIAA1324 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 42-300 of human KIAA1324 (NP_001253977.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05017A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KIAA1324 |
| Target Synonyms | EIG121; KIAA1324 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 42-300 of human KIAA1324 (NP_001253977.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6UXG2 | Immunogen Sequence |
Uniprot Id
Q6UXG2
Target Species
Human
Target Name
ELAPOR1
Target Full Name
Endosome/lysosome-associated apoptosis and autophagy regulator 1
Target Function
May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. May play a role in apoptosis and cell proliferation through its interaction with HSPA5.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Target Protein Families
UPF0577 family
Target Tissue Specificity
Expressed in normal endometrium but overexpressed in endometroid tumors.
Target Synonyms
EIG121; Estrogen induced gene 121; Estrogen-induced gene 121 protein; Hypothetical protein LOC57535; K1324_HUMAN; KIAA1324; MABA1; MGC150624; UPF0577 protein KIAA1324
Target Background
Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants.
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