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Rabbit anti-Human KIAA1324 Polyclonal Antibody

The antibody against KIAA1324 was raised in rabbit using the Fusion protein of Human KIAA1324 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-30129A

The antibody against KIAA1324 was raised in rabbit using the Fusion protein of Human KIAA1324 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-30129A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKIAA1324
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human KIAA1324Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6UXG2
Background Information
  • Uniprot Id

    Q6UXG2

  • Target Species

    Human

  • Target Name

    ELAPOR1

  • Target Full Name

    Endosome/lysosome-associated apoptosis and autophagy regulator 1

  • Target Function

    May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. May play a role in apoptosis and cell proliferation through its interaction with HSPA5.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.

  • Target Protein Families

    UPF0577 family

  • Target Tissue Specificity

    Expressed in normal endometrium but overexpressed in endometroid tumors.

  • Target Synonyms

    EIG121; Estrogen induced gene 121; Estrogen-induced gene 121 protein; Hypothetical protein LOC57535; K1324_HUMAN; KIAA1324; MABA1; MGC150624; UPF0577 protein KIAA1324

  • Target Background

    Expression of this gene is induced by estrogen and the encoded protein has been characterized as a transmembrane protein. The encoded protein has been found in to correlate with survival in certain carcinomas (PMID: 21102415) and may be important for cellular response to stress (PMID: 21072319). Alternative splicing results in multiple transcript variants.

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