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Rabbit anti-Human KIF2B Polyclonal Antibody

The antibody against KIF2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 544-673 of human KIF2B (NP_115948.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09477A

The antibody against KIF2B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 544-673 of human KIF2B (NP_115948.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09477A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKIF2B
Target SynonymsKIF2BFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, Mouse testis, Rat lung, Rat testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 544-673 of human KIF2B (NP_115948.4).Target SpeciesHuman
Immunogen SequenceNVDVRPYHRGHYPIGHEAPRMLKSHIGNSEMSLQRDEFIKIPYVQSEEQKEIEEVETLPTLLGKDTTISGKGSSQWLENIQERAGGVHHDIDFCIARSLSILEQKIDALTEIQKKLKLLLADLHVKSKVEUniprot IDQ8N4N8
Background Information
  • Uniprot Id

    Q8N4N8

  • Target Species

    Human

  • Target Name

    KIF2B

  • Target Full Name

    Kinesin-like protein KIF2B

  • Target Function

    Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Plays a role in chromosome congression.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Association with kinetochore is transient.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, MCAK/KIF2 subfamily

  • Target Tissue Specificity

    Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level).

  • Target Synonyms

    KIF2BKinesin-like protein KIF2B

  • Target Background

    Predicted to enable microtubule binding activity and microtubule motor activity. Involved in metaphase plate congression; microtubule depolymerization; and regulation of chromosome segregation. Located in intercellular bridge; mitotic spindle; and nucleolus.

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