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The antibody against KIR2DS5 was raised in rabbit using the Recombinant Human Killer cell immunoglobulin-like receptor 2DS5 protein (162-242AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against KIR2DS5 was raised in rabbit using the Recombinant Human Killer cell immunoglobulin-like receptor 2DS5 protein (162-242AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
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| Cat.No | ADC-04109A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KIR2DS5 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Killer cell immunoglobulin-like receptor 2DS5 protein (162-242AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14953 |
Uniprot Id
Q14953
Target Species
Human
Target Name
KIR2DS5
Target Full Name
Killer cell immunoglobulin-like receptor 2DS5
Target Function
Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity. Able to activate NK cells citotoxicity and cytokine production such as IFNG. Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Target Protein Families
Immunoglobulin superfamily
Target Tissue Specificity
Expressed on a discrete subset of peripheral blood NK cells.
Target Synonyms
KIR2DS5; CD158G; NKAT9Killer cell immunoglobulin-like receptor 2DS5; CD158 antigen-like family member G; MHC class I NK cell receptor; Natural killer-associated transcript 9; NKAT-9; CD antigen CD158g
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