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The antibody against KIRREL3 was raised in rabbit using the Recombinant Human Kin of IRRE-like protein 3 protein (200-343AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against KIRREL3 was raised in rabbit using the Recombinant Human Kin of IRRE-like protein 3 protein (200-343AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-03950A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KIRREL3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kin of IRRE-like protein 3 protein (200-343AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IZU9 |
Uniprot Id
Q8IZU9
Target Species
Human
Target Name
KIRREL3
Target Full Name
Kin of IRRE-like protein 3
Target Function
Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells.
Target Involvement
Mental retardation, autosomal dominant 4 (MRD4)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.; [Processed kin of IRRE-like protein 3]: Secreted.
Target Protein Families
Immunoglobulin superfamily
Target Tissue Specificity
Expressed in fetal and adult brain. Also expressed in kidney, specifically in podocytes of kidney glomeruli. Also expressed in skeletal muscle.
Target Synonyms
KIRREL3; KIAA1867; NEPH2; UNQ5923/PRO4502/PRO19814Kin of IRRE-like protein 3; Kin of irregular chiasm-like protein 3; Nephrin-like protein 2) [Cleaved into: Processed kin of IRRE-like protein 3]
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