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Rabbit anti-Human KLF17 Polyclonal Antibody

The antibody against KLF17 was raised in rabbit using the Fusion protein of Human KLF17 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-30746A

The antibody against KLF17 was raised in rabbit using the Fusion protein of Human KLF17 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-30746A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKLF17
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human KLF17Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ5JT82
Background Information
  • Uniprot Id

    Q5JT82

  • Target Species

    Human

  • Target Name

    KLF17

  • Target Full Name

    Krueppel-like factor 17

  • Target Function

    Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Sp1 C2H2-type zinc-finger protein family

  • Target Synonyms

    FLJ40160; KLF17; KLF17_HUMAN; Krueppel like factor 17; Krueppel-like factor 17; Novel zinc finger protein; RP4 675G8.1; RP4675G8.1; Zfp393; Zinc finger protein 393; ZNF393

  • Target Background

    Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gamete generation. Predicted to be located in nucleus. Predicted to be part of chromatin.

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