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The antibody against KLHL7 was raised in rabbit using the Recombinant Human Kelch-like protein 7 protein (427-586AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against KLHL7 was raised in rabbit using the Recombinant Human Kelch-like protein 7 protein (427-586AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human colon cancer using KLHL7 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using KLHL7 Antibody at dilution of 1:1002
| Cat.No | ADC-16783A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLHL7 |
| Target Synonyms | KLHL7Kelch-like protein 7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kelch-like protein 7 protein (427-586AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IXQ5 |
Uniprot Id
Q8IXQ5
Target Species
Human
Target Name
KLHL7
Target Full Name
Kelch-like protein 7
Target Function
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
Target Involvement
Cold-induced sweating syndrome 3 (CISS3); Retinitis pigmentosa 42 (RP42)
Target Subcellular Location
Nucleus. Cytoplasm.
Target Tissue Specificity
Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis.
Target Synonyms
KLHL7Kelch-like protein 7
Target Background
This gene encodes a BTB-Kelch-related protein. The encoded protein may be involved in protein degradation. Mutations in this gene have been associated with retinitis pigmentosa 42.
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