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The antibody against KLK15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human KLK15 (NP_059979.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KLK15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human KLK15 (NP_059979.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00503A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLK15 |
| Target Synonyms | ACO; HSRNASPH; KLK15 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human KLK15 (NP_059979.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | RDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC | Uniprot ID | Q9H2R5 |
Uniprot Id
Q9H2R5
Target Species
Human
Target Name
KLK15
Target Full Name
Kallikrein-15
Target Function
Protease whose physiological substrate is not yet known.
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase S1 family, Kallikrein subfamily
Target Tissue Specificity
Highest expression in the thyroid gland. Also expressed in the prostate, salivary, and adrenal glands and in the colon testis and kidney.
Target Synonyms
KLK15; Kallikrein-15; EC 3.4.21.-; ACO protease
Target Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
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