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Rabbit anti-Human KLK15 Polyclonal Antibody

The antibody against KLK15 was raised in rabbit using the Fusion protein of Human KLK15 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-31740A

The antibody against KLK15 was raised in rabbit using the Fusion protein of Human KLK15 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-31740A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKLK15
Target SynonymsKLK15 antibody; Kallikrein-15 antibody; EC 3.4.21.- antibody; ACO protease antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human KLK15Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H2R5
Background Information
  • Uniprot Id

    Q9H2R5

  • Target Species

    Human

  • Target Name

    KLK15

  • Target Full Name

    Kallikrein-15

  • Target Function

    Protease whose physiological substrate is not yet known.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Peptidase S1 family, Kallikrein subfamily

  • Target Tissue Specificity

    Highest expression in the thyroid gland. Also expressed in the prostate, salivary, and adrenal glands and in the colon testis and kidney.

  • Target Synonyms

    KLK15; Kallikrein-15; EC 3.4.21.-; ACO protease

  • Target Background

    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.

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