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Rabbit anti-Human KLK5 Polyclonal Antibody

The antibody against KLK5 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200-293 of human KLK5 (NP_001070959.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05411A

The antibody against KLK5 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200-293 of human KLK5 (NP_001070959.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05411A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKLK5
Target SynonymsSCTE; KLKL2; KLK-L2; KLK5FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesA-431ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 200-293 of human KLK5 (NP_001070959.1).Target SpeciesHuman
Immunogen SequenceFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANSUniprot IDQ9Y337
Background Information
  • Uniprot Id

    Q9Y337

  • Target Species

    Human

  • Target Name

    KLK5

  • Target Full Name

    Kallikrein-5

  • Target Function

    May be involved in desquamation.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Peptidase S1 family, Kallikrein subfamily

  • Target Tissue Specificity

    Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.

  • Target Synonyms

    HK5; Kallikrein 5; Kallikrein L2; Kallikrein like 2; Kallikrein like protein 2; Kallikrein related peptidase 5; Kallikrein-5; Kallikrein-like protein 2; Kallikrein5; KLK 5; KLK L2; KLK-L2; KLK5; KLK5_HUMAN; KLKL 2; KLKL2; SCTE; Stratum corneum tryptic enzyme; UNQ570/PRO1132

  • Target Background

    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.

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