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The antibody against KRR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human KRR1 (NP_008974.5) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against KRR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human KRR1 (NP_008974.5) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-03943A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KRR1 |
| Target Synonyms | HRB2; RIP-1; KRR1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 293T, A-431, HepG2, Mouse thymus | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human KRR1 (NP_008974.5). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q13601 | Immunogen Sequence |
Uniprot Id
Q13601
Target Species
Human
Target Name
KRR1
Target Full Name
KRR1 small subunit processome component homolog
Target Function
Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Translocates from cytoplasm to nucleus after exposure to HIV-1 virus or HIV-1 protein VPR or induction by hydrocortisone and dexamethasone in the absence of HIV-1 protein VPR (Ref.6).
Target Protein Families
KRR1 family
Target Synonyms
HIV 1 Rev binding protein 2; HIV-1 Rev-binding protein 2; HRB2; KRR1; KRR1 small subunit processome component homolog; KRR1; small subunit (SSU) processome component; homolog (yeast); KRR1_HUMAN; Rev interacting protein 1; Rev-interacting protein 1; RIP 1 ; Rip-1
Target Background
Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in chromosome; intercellular bridge; and nuclear lumen.
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