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The antibody against L3MBTL2 was raised in rabbit using the Recombinant Human Lethal(3)malignant brain tumor-like protein 2 protein (1-230AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against L3MBTL2 was raised in rabbit using the Recombinant Human Lethal(3)malignant brain tumor-like protein 2 protein (1-230AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-10237A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | L3MBTL2 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Lethal(3)malignant brain tumor-like protein 2 protein (1-230AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q969R5 |
Uniprot Id
Q969R5
Target Species
Human
Target Name
L3MBTL2
Target Full Name
Lethal(3)malignant brain tumor-like protein 2
Target Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Target Subcellular Location
Nucleus.
Target Synonyms
3bt like 2 protein; 3bt like protein; DKFZP761I141 ; H-l(3)mbt-like protein 2; H-l(3)mbt-like protein; Hl ; Hl(3)mbt like protein ; Hl(3)mbtl ; L; l(3)mbt like 2 (Drosophila) ; l(3)mbt like 2; L(3)mbt-like 2 protein; L(3)mbt-like protein 2; L3MBTL2; Lethal; Lethal(3)malignant brain tumor-like 2 protein; Lethal(3)malignant brain tumor-like protein 2; LMBL2_HUMAN
Target Background
Enables methylated histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including ectoderm development; regulation of histone modification; and stem cell proliferation. Located in nucleus.
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