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Rabbit anti-Human LAGE3 Polyclonal Antibody

The antibody against LAGE3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07510A

The antibody against LAGE3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07510A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLAGE3
Target SynonymsCVG5; ESO3; Pcc1; ITBA2; GAMOS2; DXS9879E; DXS9951E; LAGE3FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesBxPC-3, HepG2, NCI-H460ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-143 of human LAGE3 (NP_006005.2).Target SpeciesHuman
Immunogen SequenceMRDADADAGGGADGGDGRGGHSCRGGVDTAAAPAGGAPPAHAPGPGRDAASAARGSRMRPHIFTLSVPFPTPLEAEIAHGSLAPDAEPHQRVVGKDLTVSGRILVVRWKAEDCRLLRISVINFLDQLSLVVRTMQRFGPPVSRUniprot IDQ14657
Background Information
  • Uniprot Id

    Q14657

  • Target Species

    Human

  • Target Name

    LAGE3

  • Target Full Name

    EKC/KEOPS complex subunit LAGE3

  • Target Function

    Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    CTAG/PCC1 family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    LAGE3; DXS9879E; ESO3; ITBA2EKC/KEOPS complex subunit LAGE3; L antigen family member 3; Protein ESO-3; Protein ITBA2

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