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The antibody against LAMA3 was raised in rabbit using the Recombinant Human Laminin subunit alpha-3 protein (1570-1796AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against LAMA3 was raised in rabbit using the Recombinant Human Laminin subunit alpha-3 protein (1570-1796AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-07621A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LAMA3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Laminin subunit alpha-3 protein (1570-1796AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16787 |
Uniprot Id
Q16787
Target Species
Human
Target Name
LAMA3
Target Full Name
Laminin subunit alpha-3
Target Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.; Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.
Target Involvement
Epidermolysis bullosa, junctional, Herlitz type (H-JEB); Laryngoonychocutaneous syndrome (LOCS)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Target Tissue Specificity
Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expres
Target Synonyms
E170; Epiligrin 170 kDa subunit; Epiligrin subunit alpha; Kalinin B1 chain; Kalinin subunit alpha; LAMA3; LAMA3_HUMAN; LAMB3; LAMC2; Laminin gamma 2; Laminin 5 beta 3; Laminin 5 gamma 2 subunit; Laminin beta 3; Laminin subunit alpha-3; Laminin subunit beta 3; Laminin subunit gamma 2; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alpha
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