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The antibody against LAP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LAP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09378A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LAP3 |
| Target Synonyms | LAP; PEPS; LAPEP; HEL-S-106; LAP3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 260-519 of human LAP3 (NP_056991.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P28838 | Immunogen Sequence |
Uniprot Id
P28838
Target Species
Human
Target Name
LAP3
Target Full Name
Cytosol aminopeptidase
Target Function
Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Peptidase M17 family
Target Synonyms
AMPL_HUMAN; Cytosol aminopeptidase; epididymis secretory protein Li 106; HEL-S-106; LAP 3; LAP; LAP-3; Lap3; LAPEP; Leucine aminopeptidase 3; Leucyl aminopeptidase; PEPS; Peptidase S; Proline aminopeptidase; Prolyl aminopeptidase
Target Background
Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Located in cytosol; midbody; and nucleoplasm.
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