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The antibody against LARP6 was raised in rabbit using the Recombinant Human La-related protein 6 protein (294-453AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against LARP6 was raised in rabbit using the Recombinant Human La-related protein 6 protein (294-453AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-05369A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LARP6 |
| Target Synonyms | Acheron antibody; Achn antibody; FLJ11196 antibody; La ribonucleoprotein domain family member 6 antibody; La-related protein 6 antibody; LARP6 antibody; LARP6_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human La-related protein 6 protein (294-453AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BRS8 |
Uniprot Id
Q9BRS8
Target Species
Human
Target Name
LARP6
Target Full Name
La-related protein 6
Target Function
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Target Tissue Specificity
Expressed in numerous tissues.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Acheron; Achn; FLJ11196; La ribonucleoprotein domain family member 6; La-related protein 6; LARP6; LARP6_HUMAN
Target Background
Enables RNA binding activity and myosin binding activity. Involved in positive regulation of collagen biosynthetic process; positive regulation of mRNA binding activity; and positive regulation of translation. Located in nucleus. Part of polysome.
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