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The antibody against LAX1 was raised in rabbit using the Recombinant Human Lymphocyte transmembrane adapter 1 protein (107-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against LAX1 was raised in rabbit using the Recombinant Human Lymphocyte transmembrane adapter 1 protein (107-298AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-11793A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LAX1 |
| Target Synonyms | LAX1 antibody; LAX antibody; Lymphocyte transmembrane adapter 1 antibody; Linker for activation of X cells antibody; Membrane-associated adapter protein LAX antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Lymphocyte transmembrane adapter 1 protein (107-298AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IWV1 |
Uniprot Id
Q8IWV1
Target Species
Human
Target Name
LAX1
Target Full Name
Lymphocyte transmembrane adapter 1
Target Function
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Target Subcellular Location
Cell membrane; Single-pass type III membrane protein.
Target Tissue Specificity
Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.
Target Synonyms
LAX1; LAX; Lymphocyte transmembrane adapter 1; Linker for activation of X cells; Membrane-associated adapter protein LAX
Target Background
Enables SH2 domain binding activity and protein kinase binding activity. Involved in several processes, including B cell activation; negative regulation of MAP kinase activity; and negative regulation of T cell activation. Located in Golgi apparatus; cytosol; and plasma membrane. Is integral component of membrane.
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