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The antibody against LAX1 was raised in rabbit using the Human LAX1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against LAX1 was raised in rabbit using the Human LAX1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48117A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LAX1 |
| Target Synonyms | LAX1 antibody; LAX antibody; Lymphocyte transmembrane adapter 1 antibody; Linker for activation of X cells antibody; Membrane-associated adapter protein LAX antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human LAX1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IWV1 |
Uniprot Id
Q8IWV1
Target Species
Human
Target Name
LAX1
Target Full Name
Lymphocyte transmembrane adapter 1
Target Function
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Target Subcellular Location
Cell membrane; Single-pass type III membrane protein.
Target Tissue Specificity
Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.
Target Synonyms
LAX1; LAX; Lymphocyte transmembrane adapter 1; Linker for activation of X cells; Membrane-associated adapter protein LAX
Target Background
Enables SH2 domain binding activity and protein kinase binding activity. Involved in several processes, including B cell activation; negative regulation of MAP kinase activity; and negative regulation of T cell activation. Located in Golgi apparatus; cytosol; and plasma membrane. Is integral component of membrane.
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