-
Chinese (Simplified)
-
English
-
German
-
Korean
-
Spanish
Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against LDHB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LDHB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-15949A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LDHB |
| Target Synonyms | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281; HB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P07195 | Immunogen Sequence |
Uniprot Id
P07195
Target Species
Human
Target Name
LDHB
Target Full Name
L-lactate dehydrogenase B chain
Target Involvement
Lactate dehydrogenase B deficiency (LDHBD)
Target Subcellular Location
Cytoplasm. Mitochondrion inner membrane; Peripheral membrane protein.
Target Protein Families
LDH/MDH superfamily, LDH family
Target Research Area
Metabolism
Target Synonyms
Epididymis secretory protein Li 281; HEL S 281; L lactate dehydrogenase B chain; L-lactate dehydrogenase B chain; Lactate Dehydrogenase B; Lactate dehydrogenase H chain; LDH B ; LDH H; LDH heart subunit; LDH-B; LDH-H; LDHB; LDHB_HUMAN; LDHBD; LDHH; Renal carcinoma antigen NY REN 46; Renal carcinoma antigen NY-REN-46; TRG-5; TRG5
Target Background
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
Notification