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The antibody against LMTK3 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human LMTK3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against LMTK3 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human LMTK3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of 3T3 cells using LMTK3 Polyclonal Antibody
| Cat.No | ADC-36471A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LMTK3 |
| Target Synonyms | LMTK3 antibody; KIAA1883 antibody; TYKLM3 antibody; Serine/threonine-protein kinase LMTK3 antibody; EC 2.7.11.1 antibody; Lemur tyrosine kinase 3 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human LMTK3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96Q04 |
Uniprot Id
Q96Q04
Target Species
Human
Target Name
LMTK3
Target Full Name
Serine/threonine-protein kinase LMTK3
Target Function
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription. Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons.
Target Subcellular Location
Membrane; Single-pass membrane protein. Cell projection, axon. Cell projection, dendrite. Golgi apparatus membrane. Note=Punctate pattern in cell projections.
Target Protein Families
Protein kinase superfamily, Tyr protein kinase family
Target Synonyms
LMTK3; KIAA1883; TYKLM3; Serine/threonine-protein kinase LMTK3; EC 2.7.11.1; Lemur tyrosine kinase 3
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