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The antibody against LMX1A was raised in rabbit using the Recombinant Human LIM homeobox transcription factor 1-alpha protein (9-86AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against LMX1A was raised in rabbit using the Recombinant Human LIM homeobox transcription factor 1-alpha protein (9-86AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using LMX1A Antibody at dilution of 1:100
Western Blot_x000D_ | Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, A549 whole cell lysate, K562 whole cell lysate, HL60 whole cell lysate_x000D_ | All lanes: LMX1A antibody at 1:2000_x000D_ | Secondary_x000D_ | Goat polyclonal to rabbit IgG at 1/50000 dilution_x000D_ | Predicted band size: 43, 15 kDa_x000D_ | Observed band size: 43 kDa2
| Cat.No | ADC-11718A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LMX1A |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human LIM homeobox transcription factor 1-alpha protein (9-86AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TE12 |
Uniprot Id
Q8TE12
Target Species
Human
Target Name
LMX1A
Target Full Name
LIM homeobox transcription factor 1-alpha
Target Function
Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4AB is expressed in testis.
Target Synonyms
HGNC:6653; LIM homeobox protein 1.1; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX 1; LMX 1.1; LMX 1A; LMX-1.1; LMX1; LMX1.1; LMX1A; LMX1A_HUMAN; MGC87616
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