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The antibody against LOXL4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human LOXL4 (NP_115587.6) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against LOXL4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human LOXL4 (NP_115587.6) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03452A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Loxl4 |
| Target Synonyms | LOXC; LOXL4 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | BxPC-3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human LOXL4 (NP_115587.6). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96JB6 | Immunogen Sequence |
Uniprot Id
Q96JB6
Target Species
Human
Target Name
LOXL4
Target Full Name
Lysyl oxidase homolog 4
Target Function
May modulate the formation of a collagenous extracellular matrix.
Target Subcellular Location
Secreted, extracellular space.
Target Protein Families
Lysyl oxidase family
Target Tissue Specificity
Expressed in many tissues, the highest levels among the tissues studied being in the skeletal muscle, testis and pancreas. Expressed in cartilage.
Target Research Area
Signal Transduction
Target Synonyms
4833426I20Rik; FLJ21889; LOX L4; LOXC; LOXL 4; LOXL4; LOXL4_HUMAN; Lysyl oxidase homolog 4; Lysyl oxidase like 4; Lysyl oxidase like protein 4; Lysyl oxidase related C; Lysyl oxidase related protein C; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C
Target Background
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
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